MICHELIOLIDE EXERTS EFFECTS IN MYELOPROLIFERATIVE NEOPLASMS THROUGH INHIBITING STAT3/5 PHOSPHORYLATION VIA COVALENT BINDING TO STAT3/5 PROTEINS

Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins

Ruxolitinib is a cornerstone of management for some subsets of myeloproliferative neoplasms (MPNs); however, a considerable number of patients respond suboptimally.AAV9-cBIN1 gene therapy rescues chronic heart failure due to ischemic cardiomyopathy in a canine model.Here, we evaluated the efficacy of micheliolide (MCL), a natural guaianolide sesqui

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Communicating science in the COVID-19 news in the UK during Omicron waves: exploring representations of nature of science with epistemic network analysis

Abstract News media plays a vital role in communicating scientific evidence to the public during the COVID-19 pandemic.Carcass detection and consumption by facultative scavengers in forest ecosystem highlights the value of their ecosystem services.Such communication is important for convincing the public to follow social distancing guidelines and t

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COMPANY PERFORMANCE MEASUREMENT AND REPORTING METHODS

One of the priorities of economic research has been and remains the re-evaluation of the notion of performance and especially exploring and finding some indicators that would reflect as accurately as possible the subtleties of the economic entity.The main purpose of this paper is to highlight the main company performance measurement and reporting m

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